Dr. de Groot is a clinical health psychologist whose research focuses on the psychological sequelae of type 2 diabetes among adults, with a particular emphasis on the relationship between diabetes and depression. Within this area, her work focuses on two inter-related components: 1) the development of community-based treatment programs for adults with depression and type 2 diabetes using community-engaged research approaches and; 2) the identification of mechanisms that link diabetes and depression. One in four patients with diabetes will experience depression over the course of their lifetime. Depressed patients with diabetes are more likely to have impaired glycemic control, poor adherence to self-care behaviors, functional disability, increased severity of diabetes complications, health care costs and early mortality. More recent evidence from multiple prospective longitudinal cohort studies has documented that a lifetime history of depression increases the risk of type 2 diabetes in later life leading to fruitful examination of immune markers that may play a synergistic role in the development and perpetuation of type 2 diabetes and depression. Dr. de Groot's research also involves examination of CRP, IL-6 and other immune markers in pateints with type 2 diabetes and depression.