Directors

Carmella Evans-Molina, Associate Professor of Medicine at IUSM 

Associate Directors

 Sarah A. Tersey, Associate Research Professor of Pediatrics at IUSM

Services

The Islet and Physiology Core of the Indiana Diabetes Research Center provides IUSM and regional (IUB, IUPUI, and Purdue University) investigators with the capability to obtain high quality rodent pancreatic islets for study.  The Core also provides services for islet transplantation and will assist investigators who wish to perform immunohistochemistry, immunofluorescence, and/or analysis of beta cell mass on whole pancreata from mouse and rat models.  We are also pleased to offer several services for rodent metabolic characterization, including performance of insulin and glucose tolerance testing, analysis of body composition and metabolic cage analysis using the TSE System cages. The Islet and Physiology Core functions as part of the Indiana Diabetes Research Center and the IUSM Center for Diabetes and Metabolic Diseases, to foster new knowledge, support training, and promote basic and translational research in diabetes and related metabolic disorders and their complications​.

Contacts

For more information or to request services please email isletlab@iu.edu.

Fees

For more information on services or pricing please email isletlab@iu.edu

Services
Mouse Islet Isolation (1-12 mice)
Mouse Islet Isolation (13-18 mice)
Rat Islet Isolation (1- 4 rats)
Mouse Tissue Collection
Blood Glucose Measurements
Serial Blood Sampling (Per Sample)
Glucose Tolerance Test (1-10 mice)
Insulin Tolerance Test (1-10 mice)
DXA Body Mass Measurements (User pays equipment fee)
Metabolic Cage Testing (1-8 mice)
Metabolic Cage Analysis (1-8 mice)
β Cell Mass
Tissue Immunohistochemistry
Calcium (by Flex Station) (per plate)
Polyribosomal Profiling (per 6 samples)